A ten year old Eliza Dushku was chosen, after months of searching, to star in the lead role in the movie, That Night. After that, she appeared in This Boy’s Life with Leonardo DiCaprio and Robert De Niro in a role that got the child actress a lot of attention. As a teenager, Dushku was cast as the daughter of Jamie Lee Curtis and Arnold Schwarzenegger in the action thriller True Lies. Still a high schooler, she appeared along with Sarah Michelle Gellar in Buffy the Vampire Slayer.
She has reprised her role from Buffy the Vampire Slayer several times throughout her career. Dushku has worked steadily since her teenage years, appearing in films and television shows, and doing voiceover work.